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Biological and physiological aspects OF Human sexuality Human reproductive system- Like other mammals, humans are primarily grouped into either the male or female sex with a small proportion (around 1%) of intersex individuals, for whom sexual classification may not be as clear. The biological aspects of humans' sexuality deal with the reproductive system, the sexual response cycle, and the factors that affect these aspects. They also deal with the influence of biological factors on other aspects of sexuality, such as organic and neurological responses, [20] heredity, hormonal issues, gender issues, and sexual dysfunction.